about Hepatitis3 Nov 2017
4 It is one of five known hepatitis viruses: A , B , C, D , and E 8 Diagnosis is by blood testing to look for either antibodies to the virus or its RNA 1 Testing is recommended in all people who are at risk. Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver 2 During the initial infection people often have mild or no symptoms.
If the infection is left untreated for many years, some people with hepatitis C will develop scarring of the liver (cirrhosis) Over time, this can cause the liver to stop working properly. CDC’s recommendations for prevention and control of the Hepatitis C virus infection state that people should not be excluded from work, school, play, child care, or other settings because they have Hepatitis C. There is no evidence that people can get Hepatitis C from food handlers, teachers, or other service providers without blood-to-blood contact. It results from infection with the Hepatitis C virus (HCV), which is spread primarily through contact with the blood of an infected person.
The hepatitis C virus’s RNA can be identified by a type of test called polymerase chain reaction (PCR) that detects circulating virus in the blood as early as 2-3 weeks after infection, so it can be used to detect suspected acute infection with hepatitis C early infection. Blood can be tested for antibody to hepatitis C. It takes up to six months for antibodies to develop after the initial infection with hepatitis C, so screening for antibodies may miss a few newly-infected individuals. People who may have been exposed to hepatitis C in the previous 6 months should be tested for viral RNA load rather than hepatitis C antibody because antibody may not be present early in hepatitis C infection.
About 75% to 85% of people who have it develop a long-term infection called chronic hepatitis C It can lead to conditions like liver cancer and cirrhosis , or scarring of the liver This is one of the top reasons people get liver transplants. WHO recommends that all patients with hepatitis C be treated with DAA-based regimens, except for a few specific groups of people in whom interferon-based regimens can still be used (as an alternative regimen for patients with genotype 5 or 6 infection and those with genotype 3 HCV infection who also have cirrhosis). In those people who go on to develop chronic HCV infection, the infection is also often undiagnosed because the infection remains asymptomatic until decades after infection when symptoms develop secondary to serious liver damage.
Antiviral medicines can cure more than 95% of persons with hepatitis C infection, thereby reducing the risk of death from liver cancer and cirrhosis, but access to diagnosis and treatment is low. Viral load tests measure the number of viral RNA particles in the blood when someone has hepatitis C virus infection. HCV-RNA tests are used to see whether the hepatitis C virus is in your child’s blood.